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Hua Chen Selected Research

Messenger RNA (mRNA)

10/2021Shenqi Lixin Decoction improves cardiac function in rats with adriamycin-induced heart failure through modulation of PGC-1α and mitochondrial apoptosis pathway.
1/2019Adipokine Chemerin Stimulates Progression of Atherosclerosis in ApoE-/- Mice.
1/2019Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer.
11/2018Aberrant Expansion and Function of Follicular Helper T Cell Subsets in IgG4-Related Disease.
1/2018Crucial microRNAs and genes in metformin's anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis.
2/2017Expression and clinical significance of high risk human papillomavirus and invasive gene in cervical carcinoma.
1/2017NLRP3 Inflammasome Expression and Signaling in Human Diabetic Wounds and in High Glucose Induced Macrophages.
1/2017ROS-activated NLRP3 inflammasome initiates inflammation in delayed wound healing in diabetic rats.
9/2016Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network.
11/2014Colon cancer bears overexpression of OTUB1.
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Hua Chen Research Topics

Disease

114Neoplasms (Cancer)
11/2022 - 08/2002
41Inflammation (Inflammations)
07/2022 - 04/2006
25Pancreatic Neoplasms (Pancreatic Cancer)
09/2022 - 05/2008
23Fibrosis (Cirrhosis)
10/2021 - 08/2004
22Dementia (Dementias)
01/2022 - 03/2008
20Rheumatoid Arthritis
01/2022 - 07/2006
20Infections
12/2021 - 08/2006
19Wounds and Injuries (Trauma)
06/2022 - 05/2010
18Neoplasm Metastasis (Metastasis)
09/2022 - 05/2005
14Breast Neoplasms (Breast Cancer)
01/2021 - 05/2005
12Hypertension (High Blood Pressure)
10/2022 - 06/2010
12Pain (Aches)
03/2022 - 09/2005
12Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2022 - 09/2011
12Osteoarthritis
10/2021 - 07/2006
12Glioma (Gliomas)
01/2021 - 01/2008
10Immunoglobulin G4-Related Disease
01/2021 - 05/2014
10Hemorrhage
06/2020 - 09/2014
9Lung Neoplasms (Lung Cancer)
06/2022 - 08/2006
9Osteoporosis
01/2022 - 11/2011
9Heart Failure
10/2021 - 10/2006
9Hepatocellular Carcinoma (Hepatoma)
01/2021 - 03/2004
9Parkinson Disease (Parkinson's Disease)
01/2021 - 12/2010
9Carcinogenesis
11/2020 - 07/2002
9Chronic Renal Insufficiency
01/2019 - 01/2014
8Colorectal Neoplasms (Colorectal Cancer)
11/2020 - 12/2003
8Carcinoma (Carcinomatosis)
02/2017 - 08/2002
7Type 2 Diabetes Mellitus (MODY)
06/2022 - 10/2012
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2022 - 03/2018
7Diabetes Mellitus
01/2022 - 09/2005
7Hypoxia (Hypoxemia)
01/2021 - 01/2002
7Obesity
01/2021 - 06/2016
7Schizophrenia (Dementia Praecox)
01/2021 - 09/2005
6Body Weight (Weight, Body)
06/2022 - 12/2008
6Prostatic Neoplasms (Prostate Cancer)
01/2022 - 11/2007
6Hyperlipidemias (Hyperlipidemia)
01/2022 - 01/2014
6Stroke (Strokes)
01/2022 - 06/2006
6Multiple Sclerosis
01/2022 - 01/2019
6Autoimmune Diseases (Autoimmune Disease)
01/2022 - 10/2014
6Mental Disorders (Mental Disorder)
01/2021 - 04/2012
6Bipolar Disorder (Manic Depressive Psychosis)
01/2021 - 09/2013
6Leukemia
05/2018 - 08/2002
5Insulin Resistance
10/2022 - 08/2017
5Asthma (Bronchial Asthma)
03/2022 - 12/2005
5Colonic Neoplasms (Colon Cancer)
01/2022 - 04/2011
5Intervertebral Disc Degeneration
10/2021 - 10/2017
5Uterine Cervical Neoplasms (Cancer of the Cervix)
06/2021 - 12/2008
5Atherosclerosis
06/2021 - 04/2006
5Pneumonia (Pneumonitis)
10/2020 - 04/2013
5Proteinuria
01/2020 - 01/2013

Drug/Important Bio-Agent (IBA)

47Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2002
26Biomarkers (Surrogate Marker)IBA
09/2022 - 07/2005
23Pharmaceutical PreparationsIBA
01/2021 - 03/2005
18Biological ProductsIBA
12/2021 - 12/2003
16Antipsychotic Agents (Antipsychotics)IBA
01/2021 - 06/2007
14Long Noncoding RNAIBA
09/2022 - 01/2016
14CytokinesIBA
01/2022 - 03/2010
13Messenger RNA (mRNA)IBA
10/2021 - 11/2002
11EnzymesIBA
04/2022 - 08/2004
11MicroRNAs (MicroRNA)IBA
12/2021 - 09/2009
10Therapeutic UsesIBA
01/2022 - 01/2013
10LipidsIBA
12/2021 - 12/2008
10Immunoglobulin G (IgG)IBA
08/2019 - 04/2013
10GlucocorticoidsIBA
01/2019 - 10/2006
10DNA (Deoxyribonucleic Acid)IBA
04/2016 - 08/2002
9Glucose (Dextrose)FDA LinkGeneric
01/2022 - 11/2009
9CreatinineIBA
01/2022 - 01/2011
8NF-kappa B (NF-kB)IBA
10/2021 - 01/2010
7Interleukin-6 (Interleukin 6)IBA
07/2022 - 01/2018
7Oxygen (Dioxygen)IBA
01/2022 - 01/2002
7InflammasomesIBA
10/2021 - 01/2015
7AutoantibodiesIBA
10/2021 - 01/2015
7Reactive Oxygen Species (Oxygen Radicals)IBA
06/2021 - 02/2014
7artenimol (dihydroartemisinin)IBA
09/2016 - 02/2009
6Doxorubicin (Adriamycin)FDA LinkGeneric
10/2021 - 05/2007
6Cholinergic Antagonists (Anticholinergics)IBA
01/2021 - 10/2013
6AntibodiesIBA
01/2021 - 07/2006
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2020 - 12/2003
6GemcitabineFDA Link
10/2018 - 01/2010
5AntioxidantsIBA
04/2022 - 06/2016
5Peptides (Polypeptides)IBA
04/2022 - 10/2003
5ElementsIBA
03/2022 - 11/2019
5LigandsIBA
01/2022 - 10/2003
5Protein Kinases (Protein Kinase)IBA
01/2022 - 06/2014
5Antihypertensive Agents (Antihypertensives)IBA
01/2021 - 12/2008
5C-Reactive ProteinIBA
01/2021 - 01/2011
5LuciferasesIBA
12/2019 - 10/2009

Therapy/Procedure

56Therapeutics
01/2022 - 03/2005
18Radiotherapy
04/2022 - 09/2014
18Drug Therapy (Chemotherapy)
01/2022 - 10/2009
12Aftercare (After-Treatment)
02/2022 - 07/2009
10Home Nursing (Nursing, Home)
01/2020 - 01/2009
8Injections
01/2022 - 08/2006
8Arthroplasty
10/2021 - 10/2017
7Lasers (Laser)
01/2021 - 08/2002
5Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2022 - 09/2016
5Transplantation
01/2022 - 01/2013
5Operative Surgical Procedures
10/2021 - 09/2011
5Diskectomy (Discectomy)
09/2021 - 10/2017
5Bone Transplantation (Bone Grafting)
07/2021 - 08/2006
5Percutaneous Coronary Intervention
01/2021 - 09/2006